VascVita's health calculations and wellness metrics are grounded in peer-reviewed scientific research. The following sources inform our algorithms, activity thresholds, and vascular estimation models.
Arterial Stiffness Estimation
Greve SV, et al. (2016). Estimated carotid-femoral pulse wave velocity has similar predictive value as measured carotid-femoral pulse wave velocity. Journal of Hypertension, 34(7), 1279–1289.
This study validates the Greve 2 mathematical model used in VascVita to estimate pulse wave velocity (PWV), a key indicator of arterial stiffness.
Pulse Wave Estimation
Heffernan KS, et al. (2023). Association between physical activity and vascular stiffness in the general adult population. PLOS ONE, 18(5), e0285900.
This study validates the estimated pulse wave velocity (ePWV) as a simplified, high-accuracy proxy for vascular aging, enabling arterial stiffness screening using only age and blood pressure without specialized equipment.
PWV Population Reference Values
Reference Values for Arterial Stiffness' Collaboration. (2010). Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: 'establishing normal and reference values'. European Heart Journal, 31(19), 2338–2350.
Established the definitive age- and sex-specific reference values (nomograms) for pulse wave velocity, providing the clinical gold standard to distinguish normal vascular aging from stiffness driven by cardiovascular risk factors.
Exercise & Arterial Health
Ashor AW, et al. (2014). Exercise modalities and endothelial function: a systematic review and dose–response meta-analysis of randomized controlled trials. PLOS ONE, 9(10), e110034.
Research demonstrating exercise-induced reductions in arterial stiffness, establishing the 1,000 MET-min/week threshold used in activity recommendations.
Sleep & Arterial Stiffness
Wang H, et al. (2021). Sleep duration and arterial stiffness: a U-shaped association study linking short and long sleep durations with increased pulse wave velocity.
Established a U-shaped association between sleep duration and arterial stiffness, demonstrating that both short and long sleep durations are strongly associated with increased pulse wave velocity.
VascVita is a general wellness app that provides informational lifestyle insights and is not a medical device or a source of medical advice, diagnosis, or treatment. All metrics are estimates only, not medical-grade, and the app does not provide clinical monitoring, alerts, or clinician review. Always consult a qualified healthcare professional for medical concerns.